Chagasic meningoencephalitis: case report of a recently included AIDS-defining illness in Brazil.
نویسندگان
چکیده
Recently, reactivation of Chagas disease (meningoencephalitis and/or myocarditis) was included in the list of AIDS-defining illnesses in Brazil. We report a case of a 52-year-old patient with no history of previous disease who presented acute meningoencephalitis. Direct examination of blood and cerebrospinal fluid (CSF) showed Trypanosoma cruzi. CSF culture confirmed the diagnosis. Serological assays for T. cruzi and human immunodeficiency virus (HIV) were positive. Despite treatment with benznidazol and supportive measures, the patient died 24 hours after hospital admission. In endemic areas, reactivation of Chagas disease should always be considered in the differential diagnosis of meningoencephalitis among HIV-infected patients, and its presence is indicative of AIDS.
منابع مشابه
[Three-year survival of a patient with HIV and chagasic meningoencephalitis: case report].
Immunocompromised patients as those with renal transplant, hematological neoplasia or cancer and HIV/AIDS infection can suffer acute reactivation of Chagas disease. Central nervous system (CNS) evolvement (cerebral tumor or chagoma and diffuse meningoencephalitis) is similar to other opportunistic infections that present with cerebral expansive processes like toxoplasmosis or CNS primary lympho...
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The reactivation of Chagas disease in HIV infected patients presents high mortality and morbidity. We present the case of a female patient with confirmed Chagasic meningoencephalitis as AIDS-defining illness. Interestingly, her TCD4+ lymphocyte cell count was 318 cells/mm3. After two months of induction therapy, one year of maintenance with benznidazol, and early introduction of highly active a...
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We report a case of chagasic meningoencephalitis reactivation in a pregnant woman co-infected with Trypanosoma cruzi and HIV that was successfully managed with benznidazole and highly active antiretroviral therapy. Early diagnosis enabled rapid specific treatment that improved the health of the patient and her baby.
متن کاملProlonged survival and immune reconstitution after chagasic meningoencephalitis in a patient with acquired immunodeficiency syndrome Sobrevida prolongada e reconstituição imunológica depois de meningoencefalite chagásica de um paciente com síndrome de imunodeficiência adquirida
We report a case of cerebral meningoencephalitis due to Trypanosoma cruzi in a patient with acquired immunodeficiency syndrome. The patient presented with seizures and focal neurological signs. Definitive diagnosis of chagasic meningoencephalitis was made by demonstration of free trypomastigote forms in the cerebrospinal fluid. Benznidazol was prescribed with clinical and neurological improveme...
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عنوان ژورنال:
- Revista do Instituto de Medicina Tropical de Sao Paulo
دوره 46 4 شماره
صفحات -
تاریخ انتشار 2004